منابع مشابه
Metastatic colorectal cancer: systemic treatment in the new millennium.
BACKGROUND Colorectal cancer (CRC) is common in North America. Metastatic disease is present at diagnosis in 30% of the patients, and approximately half of early-stage patients will eventually present with metastatic disease. Until recently, few chemotherapy options were available to treat metastatic CRC. METHODS The authors review the results of recent clinical trials and the design of ongoi...
متن کاملSystemic therapy for colorectal cancer.
N Engl J Med 2005;352:476-87. Copyright © 2005 Massachusetts Medical Society. olorectal cancer is the third most common malignant disease and the second most frequent cause of cancer-related death in the United States, with 145,290 new cases and 56,290 deaths anticipated in 2005. 1 Worldwide, colorectal cancer is the fourth most commonly diagnosed malignant disease, with an estimated 1,023,000 ...
متن کاملEvaluation of pre-treatment serum levels of IL-7 and GM-CSF in colorectal cancer patients
Background: Survival of Colorectal cancer (CRC) patients is considerably stage-dependent therefore, early diagnosis is a pivotal factor in decreasing mortality and morbidity associated with this cancer. GM-CSF and IL-7 are reported to increase in different cancers and we aim to investigate the pre-treatment serum levels of GM-CSF and IL-7 in Iranian patients with colorectal cancer. Methods: ...
متن کاملRole of Molecular Biomarkers in Colorectal Cancer
Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...
متن کاملSystemic Treatment of Breast Cancer
Over the past 20 years we have witnessed the emergence of a new generation of aromatase inhibitors as valuable antiestrogens in the management of both advanced and early-stage breast cancer. In addition, the list of cytotoxic chemotherapeutic agents useful in the control of breast cancer has grown considerably. The emergence of anthracyclines was a major chemotherapeutic step forward in the 198...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2008
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2008.02.098